HIV Foundation Health Magnesium is vital – you need to look out for it to stay healthy

Magnesium is vital – you need to look out for it to stay healthy

Magnesium is involved in hundreds of different processes in the body. Therefore, the symptoms of a magnesium deficiency can be different. What surprising signs are possible, who is particularly at risk and how you can intelligently compensate for a magnesium deficiency.

Magnesium is particularly well known in connection with magnesium deficiency and cramps. This applies to nocturnal calf cramps, but also massive cramps in athletes. But this important role that magnesium takes on for well-functioning muscles, only reflects a tiny aspect of its very broad spectrum of activity with diverse, vital functions.

What is magnesium

Magnesium is a mineral and belongs to the group of metals. This mineral is essential. This means that the body cannot produce magnesium itself, but the mineral is vital and must therefore be supplied with the diet. It is then absorbed through the intestinal walls and gets into the blood. Any excess is excreted through the kidneys with the urine. High fat foods, oxalates and phosphates can slow down the absorption of magnesium in the intestine.

Around 25 grams of magnesium are present in the organism (in a person weighing 70 kilograms). A good half is in the bones, a little less in the muscles and only one percent in the blood. The bones also act as magnesium stores. However, the magnesium content in bones decreases over the course of life.

In addition, minerals are divided into bulk and trace elements. Magnesium is one of the bulk elements because the body needs relatively large amounts of it, unlike trace elements such as iodine and copper.

Why Magnesium is Vital

Magnesium is involved in the activation of over 300 enzymes in the body, including in the protein structure. The mineral takes on decisive tasks for energy and cell metabolism and regulates many vital functions, including:

  • Impulse transmission in muscle and nerve cells, magnesium ensures normal conduction of excitation in nerves and muscles. In connection with nerves, magnesium also supports brain functions and via the muscles, for example, the heart muscle. Adequate magnesium intake even seems to reduce the risk of sudden cardiac death, a study suggests.
  • Magnesium influences the heart rhythm and blood pressure.
  • It relaxes muscles, nerves and blood vessels and can reduce the production of stress hormones. This normalization of the excitability of nerves and the vascular tension is probably responsible for the fact that with an adequate supply of magnesium, among other things, the number of migraine attacks demonstrably decreases, as the analysis of several studies showed.
  • Magnesium can reduce the clumping of blood platelets, so it can support normal blood clotting. The risk of having a stroke decreases when the body receives enough magnesium, further research shows .
  • It is involved in the utilization of glucose and in blood sugar control. The risk of type 2 diabetes has been shown to decrease if the mineral is taken in sufficiently.
  • Magnesium is an important antagonist of calcium, prevents too much calcium from being stored, for example in muscles, but also vessels and organs. Magnesium can prevent the formation of kidney stones, which often consist of calcium oxalate.
  • In addition, magnesium can neutralize too much stomach acid somewhat and thus reduce the risk of heartburn.
  • In conjunction with calcium and vitamin D, magnesium controls the bone metabolism. Among other things, magnesium supports the activation of vitamin D in the kidneys. Magnesium is therefore an important factor in preventing osteoporosis. Already existing osteoporosis could be slowed down somewhat by adequate intake, as a study suggests.
  • The mineral regulates important messenger substances that also play a role in the mental mood. Studies show that magnesium can have a similar effect on mild depression as certain antidepressants , the selective serotonin reuptake inhibitors (SSRIs). 

Overall, these and similar studies provide strong indications that an adequate supply of magnesium, including through dietary supplements, is associated with a lower risk of numerous common diseases.

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Can California Health Insurance Rate Reviews Stop Excessive Rate Hikes?Can California Health Insurance Rate Reviews Stop Excessive Rate Hikes?

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Despite thе implementation оf rate reviews, little help іѕ seen bу millions оf consumers. California health insurance premiums continue tо skyrocket making іt hard fоr Californians tо afford health care coverage.

Evеn thоugh California саn publicly shame аnd persuade insurers tо prevent proposed increases, іt ѕtіll lacks thе power tо reject thе proposed excessive rates bу insurance companies. Thе state couldn’t еvеn stop Anthem Blue Crоѕѕ frоm increasing оnе оf іtѕ coverage rates bу 16.1 percent еvеn thоugh іt wаѕ publicly declared thаt thе planned rates wеrе excessive.

Consumers Demand California Health Insurance Rate Regulations

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Hоw Cаn Consumers Afford California Health Insurance Plans?

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At 20, 40, 60 and 70 years: how to eat healthily at any ageAt 20, 40, 60 and 70 years: how to eat healthily at any age

Sometimes the body needs more protein, sometimes more carbohydrates and after a certain age it should be less overall. If you want to eat healthily for a lifetime, you should always keep an eye on your age when shopping and cooking.

According to today’s recommendations, a healthy diet consists of plenty of fresh vegetables and fruit, good oils, as little industrially processed food as possible, economical consumption of animal products, white flour and sugar – from children to old people.

So there is only healthy and unhealthy diet, but no age-related diet. But: Over the years and depending on the situation in life, the need and utilization of nutrients change. And here age definitely plays a role. For example, the nutritionists at the University of California in San Diego have put together an overview of what to look out for .

This is what matters from 20 to 40:

The basal metabolic rate is highest in young adults, which means that the body consumes the most calories even without physical activity. At this age, many people can “eat what they want” without getting fat. At least at this age, the body forgives a few fast-food orgies and other antics.

In general, it is important to build up muscles, bones and connective tissue between the ages of 20 and 30 , also with the help of a sensible diet. Everyone can benefit from this basis in later years, when it is no longer so easy to maintain fitness.

In these years, special attention to nutrition requires more of a life circumstance for women: pregnancy.

Special dietary instructions for young pregnant women only

In addition to a diet full of high-quality nutrients and the natural avoidance of tobacco and alcohol , it is important to ensure an optimal supply of vitamins, minerals and trace elements so that the child develops well. Eating for two, on the other hand, is completely unnecessary and wrong.

Therefore, all expectant mothers should take folic acid in the first 3 months of pregnancy . Iodine tablets can also be useful. And vegans also have to pay attention to a number of micronutrients that they lack by avoiding animal foods: iron, zinc , calcium, vitamins B12, B2 and D as well as an appropriate intake of omega-3 fatty acids.

This is important from 40:

From the age of 40, the metabolism begins to slow down. While the body can usually break down too much sugar and carbohydrates by the age of 30, it loses this ability by the age of 40 at the latest. Suddenly, an unchanged diet is reflected in the stomach and hips.

Anyone who is only now finding an adequate diet can still set the course for a healthy future.

Anyone who has already eaten reasonably healthy should now pay more attention to the following elements:

  • Fruits and vegetables in bright colors – the antioxidants they contain act as cell protection with an antiaging effect in the body.
  • more whole grains on the menu
  • a (small) portion of red meat twice a week – good for building muscle , also important for women because of the prevention of iron deficiency
  • Vegetarians should pay particular attention to green leafy vegetables such as spinach, kale or Swiss chard.

Here are some things to watch out for in your 50s and 60s:

Now begins a dangerous age for cardiovascular problems such as high cholesterol and high blood pressure. Anyone who has neglected their diet and has not taken much exercise must expect type 2 diabetes .

It is now important to have a diet that keeps the blood sugar level stable and prevents deposits in the blood vessels. It should be low in cholesterol, high in fiber and slowly digestible carbohydrates, so:

  • lots of vegetables
  • little animal fat
  • no sugared soft drinks
  • little white flour products

In addition:

  • nuts
  • Good oils (olive, flaxseed)
  • Fish (omega-3 fatty acids and vitamin D)
  • Low-fat dairy products (calcium)

Changes in hormones accelerate the loss of calcium from the bones. The substitution of calcium plus vitamin D can now counteract the threat of osteoporosis . Because of the breakdown of estrogen during menopause , it occurs earlier and more frequently in women. But bone loss threatens men too.

An omega-3 supplement can benefit heart health if someone doesn’t eat sea fish. Omega-3 fatty acids stabilize the blood vessels.

Proper nutrition with 70 plus:

With age, various physiological and psychological changes occur that directly affect nutritional needs. The taste buds and appetite decrease, as does the desire to cook freshly and by yourself.

The body is less able to absorb and use many vitamins and minerals. With age, the digestive juices in the stomach change, reducing the absorption of iron, calcium, and vitamins B6, B12, and folic acid.

Long-term use of prescription drugs can decrease the absorption of certain nutrients.

Less calories, but not less nutrients

Seniors need fewer calories than younger people, but no fewer nutrients. Protein becomes important again in old age: it can delay muscle loss in old age, especially when combined with strength training.

As a rule of thumb, one gram of protein per kilogram of body weight per day . However, it should not be exclusively protein from meat, as it promotes inflammation, especially in the joints.

Because digestion becomes sluggish with age, fiber is important for the 70+ generation. A teaspoon of psyllium husks are a recommended alternative to the vegetables or whole grains that would be necessary for an optimal supply. To do this, seniors have to drink plenty, even if that is difficult for many.

Osteoarthritis in the knee: How stem cells can repair damaged cartilageOsteoarthritis in the knee: How stem cells can repair damaged cartilage

It crunches and cracks, and some movements during exercise are really painful. When the knee shows signs of wear and tear, those affected want a miracle cure that rebuilds the cartilage. Hope rests on stem cells.

  • The body’s own stem cells have a positive effect on osteoarthritis-related inflammation in the knee.
  • A study now wants to clarify whether they actually build up permanent cartilage.
  • A transplant can repair minor cartilage damage in young patients.

After a certain age, signs of wear and tear become noticeable in the knee . After the age of 30, the risk increases linearly. The painful, inflammatory breakdown of cartilage in the operating room and with an artificial knee ends 150,000 times a year. Then smooth metal has to replace the cartilage layer, which allows round, painless movements in a healthy knee.

The idea frightens many people suffering from osteoarthritis. They hope for new methods to rebuild lost cartilage: stem cells should help.

Belly fat provides the best stem cell material

The doctor uses the patient’s belly fat as a starting material. The idea behind it: stem cells can be obtained particularly easily and in relatively large numbers from vascular fat tissue. Injected at the location of the defect, they learn from the microenvironment into which cell type they should develop.

According to this principle, the doctor and stem cell researcher Eckhard Alt uses the undifferentiated cells : Stem cells from the patient’s fat tissue are processed in the operating room within an hour and injected into the patient where he needs them – for example into the osteoarthritis knee.

The founder of the “Interdisciplinary Stem Cells Research Center” in Houston and a private clinic in Munich sees stem cells as the future therapy for chronic inflammatory diseases of the musculoskeletal system – among other things.

The cell extract in the knee does not guarantee success

Some orthopedic practices that offer the procedure honestly state that it is a not generally recognized attempt at healing with no guarantee of success. Rather, it is a final experimental attempt to remedy knee problems without a joint replacement.

“In this so-called ‘point-of-care’ application, a cell extract is injected that not only consists of stem cells,” explains Oliver Pullig from the Fraunhofer Translational Center for Regenerative Medicine in Würzburg. How many stem cells that are supposed to develop into cartilage material actually get into the knee is just as little regulated as the preparation of the suctioned off belly fat.

Development of osteoarthritis

Osteoarthritis most commonly occurs on the fingers, thumbs, knees, hips and big toes.

Arthrosis is always preceded by cartilage damage. Cartilage is considered to be a “shock absorber” for the joints. Initially, the damage to the cartilage is often superficial and limited to a small area. In the advanced stage, the symptoms worsen. Tension pain occurs and the joints change.

The joints react to the cartilage damage with pain, swelling or inflammation.

Stem cells instead of knee prostheses

A Europe-wide study is currently looking for scientific evidence of the anti-osteoarthritis potential of the body’s own stem cells.

A small one with six patients in Würzburg and twelve in Montpellier, France, led to success in 2013: Almost all participants canceled their previously unavoidable operation for a knee prosthesis. “Your complaints had improved throughout,” explains Oliver Pullig. “A reconstruction of cartilage was unlikely with such a large damage.”

The follow-up study that has just begun with 153 participants at ten European locations therefore fulfills a requirement that the German study director Ulrich Nöth from the Evangelical Forest Hospital Berlin-Spandau formulated back then: Stem cell therapy is best suited for patients with middle and middle-aged osteoarthritis. You are no longer eligible for a cartilage transplant, but you are too young to have an artificial joint.

New cartilage from stem cells? A study should show it

Like the pilot study, the ADIPOA2 study uses so-called mesenchymal stem cells from the abdominal fat of each subject. These precursor cells of the connective tissue have the ability to develop into cartilage, bone or fat cells.

Biologist Oliver Pullig explains: “We take 100 milliliters of belly fat from each participant. The stem cells obtained from this are multiplied millions of times in special laboratories. That takes a good two weeks. 51 patients then receive two million of these pure stem cells injected into the joint, 51 patients receive an injection with 10 million cells and 51 patients receive a placebo. “

Results should be available by the end of 2018, and thus scientific proof of whether stem cells fulfill the hope of permanently building cartilage. The scientist is optimistic: “If successful, the therapy with stem cells as a drug could be ready for the market at the next study level. It doesn’t take five years. “

Cartilage transplant only helps to a limited extent

Another method to restore lost cartilage is transplantation, which has been tried and tested for 20 years. So far, however, it has only been successful in the case of centimeter damage in an otherwise intact knee. The operation is laborious and the healing process long.

In the first keyhole surgery, the doctor removes a small piece of healthy cartilage, hardly larger than a grain of rice. These cartilage cells are propagated in the laboratory in three to four weeks. In a second operation, the surgeon places these cells or the cartilage patch on the defective area in the knee.

After that, the knee must not be subjected to any load for six weeks, then only lightly for another six weeks. Only after a year is the joint stable enough for sport to be possible.

Cartilage from the laboratory is expensive

The transplant is only suitable for younger knee patients whose cartilage and joints are free from osteoarthritis. If this therapy is successful, it can prevent further cartilage damage and a later threatened knee prosthesis.

Then, in the long term, the costs of several thousand euros for cells grown in a laboratory will pay off.

Hyaluronic acid can at least relieve pain

If these methods are out of the question, another remedy can help: synthetic hyaluronic acid is often misunderstood as a substance for building up cartilage. However, it cannot produce worn cartilage, but serves as a lubricant and for joint care.

Orthopedic surgeons inject the moisture-retaining gel three to five times at weekly intervals. Hyaluronic acid relieves pain and promotes mobility – permanently for some patients, at least for a year or two for others. Then the treatment can be repeated.